Job Description

Join to apply for the Research Scientist Stem Cell Biology role at Vertex Pharmaceuticals

Join to apply for the Research Scientist Stem Cell Biology role at Vertex Pharmaceuticals

Position Summary:

Vertex seeks a Scientist to join the Vertex Cell and Genetic Therapies (VCGT) stem cell research group in Boston, MA. The groups mission is to discover and actualize the next generation of cell therapies for Type 1 diabetes. We are looking for a candidate with an interest in pluripotent stem cells and developmental biology with research experience in signal transduction pathways, functional proteomics, and cellular response pathways. The candidate with work closely with the Stem Cell Bio team on several discovery projects across diverse goals related to our cutting-edge stem cell derived therapeutics. The ideal candidate is scientifically independent and accustomed to taking initiative. The position requires strong communication and organization skills, as well as proven adaptability and multitasking capability.

Job Description

Position Summary:

Vertex seeks a Scientist to join the Vertex Cell and Genetic Therapies (VCGT) stem cell research group in Boston, MA. The groups mission is to discover and actualize the next generation of cell therapies for Type 1 diabetes. We are looking for a candidate with an interest in pluripotent stem cells and developmental biology with research experience in signal transduction pathways, functional proteomics, and cellular response pathways. The candidate with work closely with the Stem Cell Bio team on several discovery projects across diverse goals related to our cutting-edge stem cell derived therapeutics. The ideal candidate is scientifically independent and accustomed to taking initiative. The position requires strong communication and organization skills, as well as proven adaptability and multitasking capability.

Key Responsibilities

• Perform human pluripotent stem cell culture using both 2D and 3D culture systems
• Drive discovery research efforts in dissecting cell signaling and cell stress response pathways to optimize stem cell-islet cell differentiation.
• Lead teams use of analytical tools to evaluate molecular characteristics of stem cells and/or their differentiated stem cell-derived islets (SC-Islets) in a variety of culture systems
• Execute SOPs and contribute to stem cell differentiation campaigns (periodic weekend work is required)
• Work with cross-functional teams to plan, coordinate, and execute experiments
• Present findings to group and broader T1D teams, collaborate to summarize data into reports

Scientific And Non-scientific Skills

• Mammalian cell culture experience is required. Pluripotent stem cell culture experience (e.g., hESC and/or hiPSC) and 3D culture experience are helpful to be successful in this role
• Expertise in western blotting using Protein Simple instrumentation and other proteomic characterization techniques like ELISA assays, Luminex, and/or microarrays
• Standard molecular and cell biology techniques such as immunostaining, flow cytometry, RT-qPCR, and cell-based colorimetric or luminescence assays
• Must possess critical thinking and self-reliance to solve tasks independently
• Successful candidate will have outstanding organization and multitasking capability
• Proven track record of leading projects, both intellectually and at the bench
• Must possess flexibility to quickly pivot as projects demand

Preferred Education And Experience Levels

• Ph.D. (or equivalent degree) in molecular and cell biology, developmental biology, stem cell biology, or related disciplines and 0-3 years of relevant post-doctoral employment experience, or
• Masters Degree (or equivalent degree) in molecular and cell biology, developmental biology, stem cell biology, or related disciplines and 3+ years of relevant employment experience

Pay Range

$104,200 - $156,300

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

On-Site Designated

Flex Eligibility Status

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Seniority level

• Seniority level

  Entry level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Other

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Job Tags

Full time, Summer work, Flexible hours,

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